Neuroprotective Effects of Virally Delivered HSPs in Experimental Stroke
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چکیده
منابع مشابه
Study of the Neuroprotective Effects of Memantine in Patients with Mild to Moderate Ischemic Stroke
Introduction: Ischemic stroke is amongst the top four causes of mortality and the leading cause of disability in the world. The aim of this study was to evaluate the efficacy of a high dose memantine on neurological function of patients with ischemic stroke.Methods: In a randomized, 2 armed, open-label study, patients with mild to moderate cerebral thromboembolic event (CTEE) who admitted to Im...
متن کاملStudy of the Neuroprotective Effects of Memantine in Patients with Mild to Moderate Ischemic Stroke
Introduction: Ischemic stroke is amongst the top four causes of mortality and the leading cause of disability in the world. The aim of this study was to evaluate the efficacy of a high dose memantine on neurological function of patients with ischemic stroke.Methods: In a randomized, 2 armed, open-label study, patients with mild to moderate cerebral thromboembolic event (CTEE) who admitted to Im...
متن کاملneuroprotective effects of erythropoietin in acute ischemic stroke
background: ischemic brain strokes consisttwo‑thirdsof strokesand their complications bear a lot of disability for patient and society. in this study, we seek for effect of erythropoietin on ischemic brain stroke’s outcomes according to national institutes of health stroke scale (nihss) changes. methods: this study is a rct (randomized clinical trial). all patients with focal neurologic deficit...
متن کاملNeuroprotective effects of gelsolin during murine stroke.
Increased Ca2+ influx through activated N-methyl-D-aspartate (NMDA) receptors and voltage-dependent Ca2+ channels (VDCC) is a major determinant of cell injury following brain ischemia. The activity of these channels is modulated by dynamic changes in the actin cytoskeleton, which may occur, in part, through the actions of the actin filament-severing protein gelsolin. We show that gelsolin-null ...
متن کاملNeuroprotective effects of estrogens following ischemic stroke.
Our laboratory has investigated whether and how 17beta-estradiol (E(2)) protects the brain against neurodegeneration associated with cerebrovascular stroke. We have discovered that low, physiological concentrations of E(2), which are strikingly similar to low-basal circulating levels found in cycling mice, dramatically protect the brain against stroke injury, and consequently revealed multiple ...
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ژورنال
عنوان ژورنال: Journal of Cerebral Blood Flow & Metabolism
سال: 2005
ISSN: 0271-678X,1559-7016
DOI: 10.1038/sj.jcbfm.9600190